The 63-year-old was last contacted about 11.30am yesterday and officers found a body, believed the missing woman, about 12pm today in a nature reserve near Newcastle.
"The body of a woman was located near a waterway at Glenrock nature reserve at Kahibah," NSW Police said in a statement.
It's believed she went for a walk in the area.
The woman is yet to be formally identified.
Her cause of death is not known and police are waiting on the outcome of a coroner's report.
There were serious concerns for her welfare as she lived with conditions that required ongoing treatment.
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